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- Luciana Thiago, Selma Rumiko Tsuj, Alvaro Nagib Atallah, Maria Eduarda dos Santos Puga, and de GóisAécio Flávio TeixeiraAF.
- Faculdade de Medicina de Marília, Marília, São Paulo, Brazil. dralucianathiago@yahoo.com.br
- Sao Paulo Med J. 2011 Jan 6; 129 (1): 414541-5.
AbstractIn the Western world, calcified aortic valve stenosis is the most common form of valvular heart disease, affecting up to 3% of adults over the age of 75 years. It is a gradually progressive disease, characterized by a long asymptomatic phase that may last for several decades, followed by a short symptomatic phase associated with severe restriction of the valve orifice. Investigations on treatments for aortic valve stenosis are still in progress. Thus, it is believed that calcification of aortic valve stenosis is similar to the process of atherosclerosis that occurs in coronary artery disease. Recent studies have suggested that cholesterol lowering through the use of statins may have a salutary effect on the progression of aortic valve stenosis.
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