• Graciane Laender Moreira, Mariana Rodrigues Gazzotti, Beatriz Martins Manzano, Oliver Nascimento, Rogelio Perez-Padilla, Ana Maria Baptista Menezes, and José Roberto Jardim.
• Department of Translational Medicine, Universidade Federal de São Paulo, São Paulo, Brazil.
• Sao Paulo Med J. 2015 May 1; 133 (3): 245251245-51.

Context And ObjectiveChronic obstructive pulmonary disease (COPD) is a respiratory disease of high prevalence and socioeconomic impact worldwide. It affects approximately 16% of the population of São Paulo. The incidence of COPD is still unknown in Brazil. The aim of this study was to estimate new cases of COPD in a population-based sample in São Paulo, Brazil, using three different spirometric diagnostic criteria, and to assess the concordance between these criteria.Design And SettingProspective cohort study, in the city of São Paulo, Brazil.MethodsA questionnaire was applied and anthropometry and pre and post-bronchodilator spirometry were performed on the same subjects as in the initial PLATINO study (2003) in São Paulo. Data from this follow-up study were added to the original database of the initial phase. Incident COPD cases refer to subjects who developed the disease in accordance with each spirometric criterion during the nine-year follow-up period. The Statistical Package for the Social Sciences, version 17.0 (SPSS Inc., Chicago, IL, USA) was used in the analysis and the significance level was set at P < 0.05.Results613 subjects participated in the follow-up. New COPD cases ranged in frequency from 1.4% to 4.0%, depending on the diagnostic criterion used. The concordance between the criteria ranged from 35% to 60%.ConclusionThe incidence of COPD after a nine-year follow-up was high, but varied according to the spirometric criterion used. The agreement between the criteria for identifying new cases of the disease ranged from 35% to 60%.

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