• Sao Paulo Med J · Sep 2015

    Case Reports

    A case of tumor-like inflammatory demyelinating disease with progressive brain and spinal cord involvement.

    • Xu Zhi Peng, Li Hong Hua, Sun Zhi Qiang, and Wu Qiang.
    • Department of Neurology, Wuhan General Hospital of Guangzhou Command, Wuhan, China.
    • Sao Paulo Med J. 2015 Sep 1; 133 (5): 445449445-9.

    ContextTumor-like inflammatory demyelinating disease (TIDD) usually occurs in the brain and rarely occurs in the spinal cord. TIDD appears to be very similar to tumors such as gliomas on imaging, which may lead to incorrect or delayed diagnosis and treatment.Case ReportBecause of headache and incoherent speech, a 24-year-old Chinese male presented to our hospital with a two-week history of respiratory infections. After dexamethasone treatment, his symptoms still got worse and surgery was performed for diagnostic purposes. Histological examination revealed that the lesion was inflammatory. Further lesions appeared in the spine (T3 and T4 levels) after two months and in the right occipital lobe after three months. After intravenous immunoglobulin (IVIG) and methylprednisolone treatment, his symptoms improved.ConclusionProgressive lesions may damage the brain and spinal cord, and long-term prednisolone and IVIG therapy are beneficial in TIDD patients.

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