• A&A practice · Feb 2024

    Case Reports

    Remimazolam and Remifentanil Anesthetics for an Adolescent Patient with Stiff-Person Syndrome: A Case Report.

    • Hironobu Morita, Hirotaka Kinoshita, Masayo Kiyokawa, Tetsuya Kushikata, and Kazuyoshi Hirota.
    • From the Departments of Anesthesiology.
    • A A Pract. 2024 Feb 1; 18 (2): e01758e01758.

    AbstractStiff-person syndrome (SPS) is a rare autoimmune disease characterized by fluctuating rigidity and stiffness of the axial muscles. There are no reports on the use of remimazolam in a patient with SPS. A 16-year-old Japanese woman with SPS was scheduled to undergo intrathecal baclofen pump exchange. General anesthesia was induced and maintained using remimazolam, remifentanil, and intermittent rocuronium bromide. No intraoperative mobility or significant autonomic symptoms were observed. Additionally, electroencephalographic signature showed sufficient anesthetic depth. The patient's emergence from general anesthesia was uneventful. In conclusion, remimazolam could be considered an effective anesthetic drug for patients with SPS.Copyright © 2024 International Anesthesia Research Society.

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