• Rafael Lozano, Alejandra Montoya, Christian Razo, Austin Schumacher, Haley Confort, Spencer Pease, Darwin Jones, Stefanie Watson, and Mohsen Naghavi.
• Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
• Gac Med Mex. 2023 Jan 1; 159 (6): 465473465-473.

BackgroundBetween 2020 and 2021, Mexico documented 2.21 million fatalities, out of which 25.3% were attributable to SARS-COV-2 infection.ObjectivesTo evaluate COVID-19 mortality during 2020-2021, determine its impact on national- and state-level life expectancy at birth, and in a group of selected countries of the region, as well as to analyze it according to sociodemographic profiles.Material And MethodsData from the Global Burden of Disease 2021 study were used to report mortality, the impact on life expectancy and underlying causes between 2019 and 2021. These data were evaluated from the perspective of response to the pandemic and according to the sociodemographic structure based on a quadratic regression model.ResultsBetween 2020 and 2021, 708,971 excess deaths were recorded, which decreased life expectancy at birth by 4.6 years; 76% of this reduction was attributed to COVID-19. The COVID-19 mortality rate was higher than expected according to the sociodemographic conditions of the states.ConclusionsIn Mexico and the countries of the region, the pandemic was devastating and generated regressions in life expectancy at birth, which varied from two to nine years. It is not clear why the effect was so different between countries and within Mexico.Copyright: © 2023 Permanyer.

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