• Jong-Chie Claudia Tien, Yi Hao Edgarton Ching, Hui Li Tan, Jun Jie Lee, and Kah Lai Carrie Leong.
• Division of Anesthesiology, Department of Surgical Intensive Care, Singapore General Hospital, Singapore.
• Singapore Med J. 2024 Feb 23.

IntroductionIn-hospital cardiac arrest (IHCA) is a significant healthcare burden with a paucity of data in Singapore. Various factors, including time of cardiac arrest, affect survival from acute resuscitation.MethodsThis was a retrospective cohort study that evaluated the characteristics of patients who sustained an IHCA, including the Cardiac Arrest Survival Post Resuscitation In-hospital (CASPRI) scores, and the impact of arrest time in 220 consecutive cardiac arrests occurring in a tertiary hospital. The primary outcome was rate of return of spontaneous circulation (ROSC) post-IHCA, and the secondary outcome was 90-day survival.ResultsThe ROSC rate among patients with IHCA out of and during office hours was 69.5% and 75.4%, respectively (odds ratio [OR] 0.74, 95% confidence interval [CI] 0.39-1.42). There were no statistically significant differences between the CASPRI scores of both groups. After adjusted analysis, the OR of ROSC post-IHCA out of office hours as compared to that during office hours was 0.78 (95% CI 0.39-1.53). The 90-day survival rate of patients who had an IHCA out of and during office hours was 25.7% and 34.6%, respectively (OR 0.65, 95% CI 0.32-1.34). The adjusted OR of 90-day survival was 0.66 (0.28-1.59).ConclusionThe results of this observational study did not show an association between the timing of cardiac arrest and the rate of ROSC or 90-day survival.Copyright © 2024 Copyright: © 2024 Singapore Medical Journal.

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