• BMC anesthesiology · Feb 2024

    Case Reports

    Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain.

    • Qing Li, Yan-Ling Long, Yun-Wu He, Hui Long, Zhen-Ping Xiao, Yong-Lin Li, Wu-Zhou Yang, Li-Ping Jiang, Wei Gao, and Cong Zou.
    • Department of Pain and Rehabilitation, The Second Affiliated Hospital, University of South China, Hengyang, Hunan, 421001, China.
    • BMC Anesthesiol. 2024 Feb 26; 24 (1): 7777.

    BackgroundExtensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics.Case PresentationThe present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine.ConclusionsThe patient achieved a good quality of life during the one-month follow-up period.© 2024. The Author(s).

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