• SeyedHadi SamimiArdestani, Mohammadreza Firouzifar, Maliheh Akbarpour, Karimi YarandiKouroshKDepartment of Neurosurgery, School of Medicine, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran., and SeyedMohammadmehdi SamimiArdestani.
• Otorhinolaryngology Research Center, AmirAlam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
• World Neurosurg. 2024 May 1; 185: e662e667e662-e667.

BackgroundBrain abscesses caused by sinonasal infections have become more common during the coronavirus pandemic, particularly due to the increase in sinonasal mucormycosis. This study aimed to evaluate the efficacy and safety of endoscopic endonasal brain abscess drainage as a therapeutic technique for these cases.MethodsClinical outcomes and retrospective evaluations were performed in patients who underwent endoscopic endonasal brain abscess drainage between May 2019 and August 2022. A total of 7 patients diagnosed with 9 brain abscesses caused by sinonasal infections were included in the study. The main outcome of this study was to evaluate the success and safety of this technique.ResultsThe average age of the patients was 40.71 ± 14.17 years. The most common symptom observed in these patients was nasal discharge, and the frontal lobe was the most common site of abscess. Notably, the majority of cases were associated with COVID-19.ConclusionsBased on the results of this study, endoscopic endonasal brain abscess drainage is considered a viable treatment option for skull base brain abscesses caused by sinonasal infections. Further research in this field can help establish this technique as a mainstay approach for managing brain abscesses at the skull base.Copyright © 2024 Elsevier Inc. All rights reserved.

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