• Internal medicine · Oct 2024

    Review Case Reports

    Kluyvera georgiana Bacteremia Due to Acute Cholangitis: A Report of the First Known Case and a Literature Review.

    • Go Endo, Sachiko Kanai, Hiroto Nishio, Hideki Hashimoto, Yoshimi Higurashi, Yusuke Nomura, Yousuke Nakai, and Mitsuhiro Fujishiro.
    • Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Japan.
    • Intern. Med. 2024 Oct 1; 63 (19): 268926932689-2693.

    AbstractWe herein present the first known case of bacteremia caused by Kluyvera georgiana in a 67-year-old female undergoing chemotherapy for recurrent pancreatic cancer. The patient underwent choledochojejunotomy and thereafter developed ascending cholangitis. The diagnosis of K. georgiana was confirmed using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. A literature review of Kluyvera spp. infections indicated potential risk factors including an underlying malignancy and immunosuppression. Although Kluyvera spp. infections are typically sensitive to antibiotics, multidrug resistance is possible. This case highlights the importance of the early diagnosis and treatment of K. georgiana and its associated risk factors.

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