• Internal medicine · Oct 2024

    Case Reports

    Severe Left Main Coronary Artery Stenosis and Aortic Regurgitation in a Patient Presenting with Takayasu Arteritis.

    • Akiko Tanihata, Atsushi Shibata, Kazutoshi Teragaki, Toshitake Yoshida, Ryoko Kitada, Akimasa Morisaki, Asahiro Ito, Yasuhiro Izumiya, and Daiju Fukuda.
    • Department of Cardiovascular Medicine, Osaka Metropolitan University Graduate School of Medicine, Japan.
    • Intern. Med. 2024 Oct 1; 63 (19): 264126462641-2646.

    AbstractWe herein report the case of a 46-year-old woman with Takayasu arteritis (TA), severe stenosis in the left main coronary artery (LMCA), and severe aortic regurgitation. Prednisolone and tacrolimus were initiated as TA treatments. Two months after initiating medical therapy, the aortic regurgitation severity improved to a moderate grade, although there was no obvious improvement in LMCA stenosis. Thus, after confirming the resolution of inflammation, we performed coronary artery bypass grafting alone without any aortic valve intervention. In TA patients with severe LMCA stenosis, surgical management of the coronary artery should therefore be considered only after successfully administering anti-inflammatory therapy.

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