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- Takahiro Shimizu, Yu Nagashima, Takashi Matsukawa, Akihiko Mitsutake, Mizuho Kawai, Yurino Horiuchi, Keishi Yokoyama, Kensuke Takaoka, Yuya Kurihara, Kazuhiro Toyama, Kaori Sakuishi, Mineo Kurokawa, and Tatsushi Toda.
- Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
- Intern. Med. 2024 Oct 15; 63 (20): 285328562853-2856.
AbstractPost-transplant lymphoproliferative disorders (PTLDs) are lymphoproliferative diseases that occur after solid organ transplantation or hematopoietic stem cell transplantation (HSCT). The development of PTLD is often associated with reactivation of Epstein-Barr virus (EBV). A 26-year-old woman with a history of HSCT and total-body irradiation developed spinal cord hemorrhage from a radiation-induced cavernous hemangioma (RICH) shortly after the development of classical Hodgkin lymphoma PTLD with EBV reactivation. Although little is known about the factors leading to hemorrhagic events from spinal cord RICH, we suspect that EBV reactivation may have been a factor contributing to the hemorrhage in the present case.
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