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Croatian medical journal · Feb 2024
Case ReportsGamma knife thalamotomy in treating refractory tremor: initial clinical experience in Croatia.
- Slaven Lasić, Sergej Marasanov, Marjan Rožanković, and Petra Bago Rožanković.
- Petra Bago Rožanković, Department of Neurology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, Croatia, pbagoroz@kbd.hr.
- Croat. Med. J. 2024 Feb 29; 65 (1): 596459-64.
AbstractTremor refractory to pharmacological therapy significantly reduces the patient´s quality of life, often leading to early retirement and social isolation. Gamma knife (GK) stereotactic radiosurgery of the unilateral thalamic ventral intermediate nucleus is an advanced, minimally invasive surgical procedure for symptomatic tremor suppression. Due to the restricted availability of this type of treatment, literature data on its efficacy and safety are lacking. We present two patients with severe, disabling tremor (one with parkinsonian and one with essential tremor) successfully treated with GK thalamotomy, performed in Croatia for the first time. GK thalamotomy should be considered in patients with refractory tremors and contraindications for deep brain stimulation.
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