• Internal medicine · Jan 2024

    Case Reports

    Successful Management of a Pregnant Patient with Danon Cardiomyopathy.

    • Wataru Inoue, Hirohiko Motoki, Koji Yoshie, and Koichiro Kuwahara.
    • Department of Cardiovascular Medicine, Shinshu University School of Medicine, Japan.
    • Intern. Med. 2024 Jan 1; 63 (5): 681686681-686.

    AbstractA 25-year-old woman with left ventricular (LV) dysfunction became pregnant during the diagnostic period. Decompensated heart failure with frequent ventricular arrhythmias necessitated hospitalization in the 21st week of pregnancy. Under careful monitoring, diuretics and sotalol were added to her ongoing treatment of carvedilol and spironolactone due to the risk of hemodynamic collapse. An emergency cesarean section was performed in the 32nd week after the detection of rapid nonsustained ventricular tachycardia. Subsequent genetic testing revealed that the LV dysfunction was associated with Danon cardiomyopathy. This case highlights the importance of careful pregnancy management with LV dysfunction along with early genetic testing.

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