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Case Reports
Paraneoplastic Cerebellar Degeneration Leading to an Early Diagnosis of Peritoneal Serous Papillary Carcinoma.
- Tsutomu Yasuda, Jun Shimizu, Toji Miyagawa, Yuri Tsutsumi, Takeshi Iwatsubo, and Shoji Tsuji.
- Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan.
- Intern. Med. 2024 Oct 1; 63 (19): 267926822679-2682.
AbstractA 77-year-old female with a subacute progression of ataxia and serum anti-Yo antibodies was suspected to have paraneoplastic cerebellar degeneration (PCD). An examination of an underlying cancer showed no abnormality in the gynecological organs, but the findings did show a mass in the Douglas fossa. The mass was resected and diagnosed as stage IIB peritoneal serous papillary carcinoma (PSPC), a rare gynecologic cancer that is difficult to diagnose in the early stages. PCD was treated with intravenous immunoglobulin (IVIG). For an early diagnosis and treatment, PSPC should be included in the list of malignancies that cause PCD with anti-Yo antibodies.
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