• Internal medicine · Nov 2024

    Case Reports

    A Case of Refractory Gastroesophageal Reflux Disease Successfully Treated with Endoscopic Anti-gastroesophageal Reflux Mucosal Resection by the ESD-G Method (with video).

    • Shun Sasaki, Kazuhiro Ota, Taro Iwatsubo, Noriaki Sugawara, Akitoshi Hakoda, Hironori Tanaka, Yosuke Mori, Toshihisa Takeuchi, Kazuhide Higuchi, and Hiroki Nishikawa.
    • Second Department of Internal Medicine, Osaka Medical and Pharmaceutical University, Japan.
    • Intern. Med. 2024 Nov 1; 63 (21): 292329272923-2927.

    AbstractA 70-year-old man who had undergone treatment for gastroesophageal reflux disease (GERD) by a family doctor presented to our hospital with severe heartburn and dysphagia despite taking vonoprazan (20 mg) for 3 months. A diagnosis of vonoprazan-refractory nonerosive reflux disease was made based on esophagogastroduodenoscopy and esophageal function examinations. The patient elected to undergo endoscopic treatment for GERD. Therefore, we performed endoscopic treatment using the endoscopic submucosal dissection (ESD-G) technique developed at our institution. After endoscopic treatment, his GERD symptoms disappeared and he no longer required GERD-related medications. An examination of his esophageal function revealed the improvement of items related to GERD.

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