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- Bao Wu, Chongming Wu, Dandan Li, Zhanmin Yang, Ying Liu, Hai-Xia Zhang, Hong-Wu Xin, and Yuqin Bai.
- Department of Histology and Embryology, School of Basic Medicine, Chifeng University, China.
- Intern. Med. 2024 Oct 15; 63 (20): 278127852781-2785.
AbstractOvary microcystic stromal tumor (MCST) is an extremely rare subtype of sex cord-stromal neoplasm, and only 57 cases have been reported. We herein report a unique case of ovarian MCST with positive nestin expression in a 39-year-old Chinese woman. The tumor showed microcystic stromal histological structures and characteristically expressed the CD10, WT-1, and Ki67 proteins. A molecular analysis identified a point mutation (c.110C > T) in exon 3 of the CTNNB1 gene. To our knowledge, no report has described a case of ovarian MCST with positive staining for nestin protein. Our study provides new insights into the tumor biology of ovarian MCST.
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