• Natascha Sommer, Klaas Franzen, Stefan Andreas, Wulf Pankow, Wilfried Kunstmann, and Reiner Hanewinkel.
• Medizinische Klinik II, Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Gießen and Marburg Lung Center (UGMLC), Mitglied des Deutschen Zentrums für Lungenforschung (DZL), Justus-Liebig-Universität Gießen.
• Dtsch. Med. Wochenschr. 2024 May 1; 149 (11): 646653646-653.

Background Almost all e-cigarettes contain flavorings that make the product more attractive. In the evaluation of e-cigarettes on health, flavors have so far played a subordinate role.Method Selective literature search in PubMed, supplemented by legal regulations on the use of flavors in e-cigarettes.Results Flavors make it easier to start using e-cigarettes and have a consumption-promoting effect. Deeper inhalation increases nicotine uptake and the absorption of toxic substances from the e-cigarette liquid. For some flavors, pathological effects have been demonstrated in addition to other toxic components of the e-cigarette. To date, no toxicological analyses are available for the vast majority of flavors contained in e-cigarettes.Conclusions The proven consumption-promoting effect and the health risks that can be extrapolated from preclinical data are significant for the political discussion of a ban on flavors for e-cigarettes, analogous to the ban on flavors in tobacco products already in force.Thieme. All rights reserved.

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