• SáMarcus Villander Barros de OliveiraMVBO0000-0003-1257-6958Royal Portuguese Charitable Hospital, Royal Medical Clinic - Recife (PE), Brazil.Aggeu Magalhães Institute, Oswaldo Cruz Foundation, Department of Parasitology and Immunology - Recife (PE), Brazi, Clarice Neuenschwander Lins de Morais, Rafaela Silva Guimarães Gonçalves, Camila Sarteschi, and Luydson Richardson Silva Vasconcelos.
• Royal Portuguese Charitable Hospital, Royal Medical Clinic - Recife (PE), Brazil.
• Rev Assoc Med Bras (1992). 2024 Jan 1; 70 (2): e20230688e20230688.

ObjectiveThe aim of this study was to assess the performance of the CALL Score tool in predicting the death outcome in COVID-19 patients.MethodsA total of 897 patients were analyzed. Univariate and multivariate logistic regression analyses were conducted to determine the association between characteristics of the CALL Score and the occurrence of death. The relationship between CALL Score risk classification and the occurrence of death was also examined. Receiver operating characteristic curve analysis was performed to identify optimal cutoff points for the CALL Score and the outcome.ResultsThe study revealed that age>60 years, DHL>500, and lymphocyte count ≤1000 emerged as independent predictors of death. Higher risk classifications of the CALL Score were associated with an increased likelihood of death. The optimal CALL Score cutoff point for predicting the death outcome was 9.5 (≥9.5), with a sensitivity of 70.4%, specificity of 80.3%, and accuracy of 80%.ConclusionThe CALL Score showed promising discriminatory ability for death outcomes in COVID-19 patients. Age, DHL level, and lymphocyte count were identified as independent predictors. Further validation and external evaluation are necessary to establish the robustness and generalizability of the CALL Score in diverse clinical settings.

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