• Zoe Lindenfeld, Kevin Chen, Supriya Kapur, and Ji E Chang.
• Department of Public Health Policy and Management, School of Global Public Health, New York University, New York, NY, USA. zll213@nyu.edu.
• J Gen Intern Med. 2024 Jul 1; 39 (9): 163216411632-1641.

BackgroundIndividuals with substance use disorders (SUDs) have increased risk for developing chronic conditions, though few studies assess rates of diagnosis of these conditions among patients with SUDs.ObjectiveTo compare rates of undiagnosed hypertension and diabetes among patients with and without an SUD.DesignCross-sectional analysis using electronic health record (EHR) data from 58 primary care clinics at a large, urban, healthcare system in New York.ParticipantsPatients who had at least two primary care visits from 2019-2022 were included in our patient sample. Patients without an ICD-10 hypertension diagnosis or prescribed hypertension medications and with at least two blood pressure (BP) readings ≥ 140/90 mm were labeled 'undiagnosed hypertension,' and patients without a diabetes diagnosis or prescribed diabetes medications and with A1C/hemoglobin ≥ 6.5% were labeled 'undiagnosed diabetes.'Main MeasuresWe calculated the mean number of patients with and without an ICD-10 SUD diagnosis who were diagnosed and undiagnosed for each condition. We used multivariate logistic regression to assess the association between being undiagnosed for each condition, and having an SUD diagnosis, patient demographic characteristics, clinical characteristics (body mass index, Elixhauser comorbidity count, diagnosed HIV and psychosis), the percentage of visits without a BP screening, and the total number of visits during the time period.Key ResultsThe percentage of patients with undiagnosed hypertension (2.74%) and diabetes (22.98%) was higher amongst patients with SUD than patients without SUD. In multivariate models, controlling for other factors, patients with SUD had significantly higher odds of having undiagnosed hypertension (OR: 1.81; 95% CI: 1.48, 2.20) and undiagnosed diabetes (OR: 1.93; 1.72, 2.16). Being younger, female, and having an HIV diagnosis was also associated with significantly higher odds for being undiagnosed.ConclusionsWe found significant disparities in rates of undiagnosed chronic diseases among patients with SUDs, compared with patients without SUDs.© 2024. The Author(s), under exclusive licence to Society of General Internal Medicine.

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