• Jessica A Palakshappa, Jane A E Batt, Sue C Bodine, Bronwen A Connolly, Jason Doles, Jason R Falvey, Lauren E Ferrante, D Clark Files, Michael O Harhay, Kirsten Harrell, Joseph A Hippensteel, Theodore J Iwashyna, James C Jackson, Meghan B Lane-Fall, Michelle Monje, Marc Moss, Dale M Needham, Matthew W Semler, Shouri Lahiri, Lars Larsson, Carla M Sevin, Tarek Sharshar, Benjamin Singer, Troy Stevens, Stephanie P Taylor, Christian R Gomez, Guofei Zhou, Timothy D Girard, and Catherine L Hough.
• Wake Forest University School of Medicine, Winston-Salem, North Carolina.
• Am. J. Respir. Crit. Care Med. 2024 Jun 1; 209 (11): 130413131304-1313.

AbstractAcute respiratory distress syndrome (ARDS) is associated with long-term impairments in brain and muscle function that significantly impact the quality of life of those who survive the acute illness. The mechanisms underlying these impairments are not yet well understood, and evidence-based interventions to minimize the burden on patients remain unproved. The NHLBI of the NIH assembled a workshop in April 2023 to review the state of the science regarding ARDS-associated brain and muscle dysfunction, to identify gaps in current knowledge, and to determine priorities for future investigation. The workshop included presentations by scientific leaders across the translational science spectrum and was open to the public as well as the scientific community. This report describes the themes discussed at the workshop as well as recommendations to advance the field toward the goal of improving the health and well-being of ARDS survivors.

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