• Cochrane Db Syst Rev · Jan 2004

    Aspirin for primary prevention of coronary heart disease.

    • Peter Pr Jackson, Mohsen Aarabi, and Erica Wallis.
    • Clinical Pharmacology and Therapeutics, Royal Hallamshire Hospital, Sheffield, UK.
    • Cochrane Db Syst Rev. 2004 Jan 1 (1).

    UnlabelledThis is the protocol for a review and there is no abstract. The objectives are as follows: To determine the effects, both harmful and beneficial of aspirin in the primary prevention of coronary heart disease.Primary QuestionsDoes aspirin prevent fatal and non-fatal CHD in people without symptomatic vascular disease? Does aspirin reduce all-cause and cardiovascular mortality?Secondary QuestionsAre the effects of aspirin, be they harmful or beneficial, affected by underlying risk of CHD? Do the major adverse effects of Aspirin ever outweigh its benefit and is this balance affected by underlying CHD risk?

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