• Wien. Klin. Wochenschr. · Dec 2012

    Comparative Study

    Positive end-expiratory pressure lung recruitment: comparison between lower inflection point and ultrasound assessment.

    • Bojan Rode, Marinko Vučić, Mladen Siranović, Ana Horvat, Helena Krolo, Mijo Kelečić, and Aleksandar Gopčević.
    • Department of Anaesthesiology and Intensive Care, University Hospital Center Sisters of Mercy, Vinogradska 29, 10000, Zagreb, Croatia. bojan.rode@zg.t-com.hr
    • Wien. Klin. Wochenschr. 2012 Dec 1;124(23-24):842-7.

    BackgroundMaintenance of the open lung alveoli in the expiration on mechanical ventilation in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) remains challenging despite advances in lung imaging. The inspiratory lower inflection point (LIP) on the ventilator pressure-volume (P-V) curve estimates the required end-expiratory pressure for recruitment of alveolar consolidation. Alternatively, the end-expiratory pressure for recruitment of crater-like subpleural alveolar consolidation could be simply followed with ultrasound. These two methods for setting the ventilators positive end-expiratory pressure (PEEP) were compared.MethodsThe observational study in surgical/neurosurgical intensive care between October 2009 and November 2011 included 17 deeply sedated or relaxed patients. LIP was measured with continuous low-flow method, as a pressure in cmH(2)O. Expiratory levelling between lower border of subpleural consolidation and adjacent pleural line, which means lung recruitment, was followed with linear ultrasound probe. PEEP in cmH(2)O at which the levelling occurs was compared with LIP pressure.ResultsLIP pressure never exceeds the PEEP for recruitment of subpleural consolidations followed with ultrasound. A significant correlation (r = 0.839; p < 0.05) was found between two methods.ConclusionsIn this study, positive end-expiratory pressures for recruitment of subpleural consolidations followed by ultrasound always exceed the pressures measured with LIP. Respecting this, ultrasound method could be the guide for PEEP lung recruitment.

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