• Vaibhav Vats, Vrunda Kulkarni, Muhammad Ashir Shafique, Abdul Haseeb, Mustafa Arain, Muhammad Armaghan, Faraz Arshad, Aleena Maryam, Behrooz Shojai Rahnama, Iman Moradi, Kanika Ahuja, Amer Kamal, Zaid Salameh, Mahlail Ahmed, and Dalia Mehmood.
• Department of Medicine, Smt. Kashibai Navale Medical College & General Hospital, Pune, India.
• Ir J Med Sci. 2024 Aug 1; 193 (4): 178717951787-1795.

BackgroundRecent studies have suggested an association between sleep duration and cardiovascular diseases; however, the link to AF is inconclusive. This study aimed to explore the relationship between sleep duration and AF by conducting a systematic review and meta-analysis of primary studies to provide evidence of the link between insufficient sleep and AF.MethodsA review of the existing literature was conducted to identify the primary studies that examined the association between AF and sleep duration. The inquiry spanned databases, including PubMed, Embase, MEDLINE, and Google Scholar, from their inception through October 2023.ResultsMeta-analysis revealed a statistically significant association (p < 0.01) between shorter sleep duration and the incidence of AF (hazard ratio (HR), 1.18; 95% CI, 1.03-1.34; I2 = 89%). Conversely, longer sleep duration did not exhibit a statistically significant association with the incidence of AF (HR, 1.03; 95% CI, 0.92-1.14; I2 = 66%, p = 0.02). The sensitivity analysis demonstrated reduced heterogeneity after excluding specific studies.ConclusionInsufficient sleep duration was associated with an increased risk of AF, whereas a longer sleep duration did not show a significant correlation. Standardized methods for sleep assessment and AF diagnosis as well as adjustments for confounding factors are suggested for future studies to improve the clarity and understanding of these associations.© 2024. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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