• Annals of Saudi medicine · May 2013

    Case Reports

    Heterosexual precocity: rare manifestation of virilizing adrenocortical oncocytoma.

    • Sridhar Subbiah, Uma Nahar, Ram Samujh, and Anil Bhansali.
    • Department of Endocrinology, Post Graduate Institute of Medical Education and Research, Chandigarh, India. drsridharjipmer@gmail.com
    • Ann Saudi Med. 2013 May 1; 33 (3): 294297294-7.

    AbstractAdrenocortical oncocytomas are extremely rare, and most of the tumors are benign and nonfunctioning. To our knowledge, only 30 cases have been reported in English published studies, and most patients are 40 to 60 years of age. So far, in the pediatric age group, only three cases of functioning adrenocortical oncocytoma have been reported. We report a case of functioning adrenocortical oncocytoma in a 3 1/2-year-old female child who presented with premature pubarche, clitoromegaly, and increased serum dehydroepiandrosterone sulfate and testosterone. She was managed successfully with right adrenalectomy, and the tumor histology was consistent with adrenal oncocytoma.

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