• Semin Respir Crit Care Med · Jun 2024

    Review

    Pleural Diseases in Connective Tissue Diseases.

    • Hui Guo, Beenish Iqbal, and Najib M Rahman.
    • Department of Respiratory and Sleep Medicine, The Alfred Hospital, Melbourne, VIC, Australia.
    • Semin Respir Crit Care Med. 2024 Jun 1; 45 (3): 305315305-315.

    AbstractConnective tissue diseases (CTD) are heterogeneous, immune-mediated inflammatory disorders often presenting with multiorgan involvement. With the advent of high-resolution computed tomography, CTD-related pleuritis-pleural thickening and effusion-is now increasingly recognized early in the disease trajectory. The natural history of CTD-related pleural effusions varies from spontaneous resolution to progressive fibrothorax with ventilatory impairment. Treatment of the underlying CTD is necessary to manage the pleural disease. Depending on the degree of symptom burden and physiological insult, specific treatment of pleural disease can include monitoring, repeated aspirations, systemic anti-inflammatory medication, and surgical decortication.Thieme. All rights reserved.

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