• Internal medicine · Nov 2024

    Case Reports

    A case of autoimmune encephalitis in a patient with a solitary intracranial plasmacytoma.

    • Keisuke Mizutani, Keita Sakurai, Yuto Uchida, Ken Hashimoto, Tomohiro Kajiguchi, Yukitoshi Takahashi, Hiroyuki Yuasa, Koji Takada, and Noriyuki Matsukawa.
    • Department of Neurology, Toyokawa City Hospital, Japan.
    • Intern. Med. 2024 Nov 15; 63 (22): 309331003093-3100.

    AbstractA 65-year-old woman presented with fever and abnormal behavior. Magnetic resonance imaging showed swelling of the left medial temporal lobe and an intracranial extra-axial occipital tumor. While her neurological symptoms improved after the administration of corticosteroid therapy under the suspicion of autoimmune encephalitis, the occipital tumor unexpectedly shrank, and the diagnosis of a solitary plasmacytoma was confirmed by biopsy. Additional examinations revealed elevated anti-glutamate receptor antibodies in the cerebrospinal fluid. The patient was diagnosed with autoimmune encephalitis concurrent with an intracranial solitary plasmacytoma. Central nervous system involvement can be considered a neurological complication in patients with a solitary plasmacytoma.

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