• Jorge Sanchez, Andres Sánchez, and Ricardo Cardona.
• Group of Clinical and Experimental Allergy, IPS Universitaria Universidad de Antioquia. Medellin, Colombia.
• Colomb Medica. 2018 Jun 30; 49 (2): 169174169-174.

BackgroundEpidemiological studies have shown that children who grow up on traditional farms are protected from allergic diseases. However, less is known about if the environment influences the pharmacotherapy in these patients.ObjectiveTo compare the treatment of asthmatic and rhinitis children from urban and rural areas in Medellín, Colombia.MethodsDuring one year, we follow up a group of children (6 to 14 years) with diagnostic of asthma or rhinitis living for more than five years in urban or rural area. A questionnaire with socio-demographic characteristics, pharmacotherapy treatments, was obtained each three months. Atopy evaluation, spirometry and clinical test for asthma and rhinitis severity were done at the beginning and one year later.ResultsEighty six point four percent patients completed the follow up (rural n: 134, urban n: 248). Patients in rural location required less salbutamol (p: 0.01), visit to emergency department (p <0.01) and have a less number of patients with FEV1 <80% (p: 0.05). For clinical control rural children require less pharmacotherapy than urban children (p: 0.01) and more patients with rhinitis (18% vs 8% p: 0.03) and asthma (23% vs 12% p: 0.01) in the rural group could suspended pharmacotherapy. Atopy (p: <0.07) and poli-sensitization (p: <0.08) was a little higher in urban than rural area. We observe that poverty/unhygienic indicators were risk factors for higher levels of specific IgE among patients from urban area.ConclusionPatients with respiratory allergies located in urban area require more pharmacotherapy and have less clinical response than rural children.

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