• Clinics · Dec 2012

    Randomized Controlled Trial

    Effects of Brazilian Cardioprotective Diet Program on risk factors in patients with coronary heart disease: a Brazilian Cardioprotective Diet randomized pilot trial.

    • Bernardete Weber, Andrea Polo Galante, Angela Cristine Bersch-Ferreira, Camila Ragne Torreglosa, Vitor Oliveira Carvalho, VictorElivane da SilvaEda S, Jose Amalth do Espírito-Santo, Maria Beatriz Ross-Fernandes, Rafael Marques Soares, Rosana Perim Costa, Enilda de Sousa Lara, Anna Maria Buehler, and Otávio Berwanger.
    • Hospital do Coração (IEP-HCor), Research Institute, São Paulo/SP, Brazil. bweber@hcor.com.br
    • Clinics (Sao Paulo). 2012 Dec 1; 67 (12): 140714141407-14.

    ObjectiveTo evaluate the effectiveness of the Brazilian Cardioprotective Diet Program in reducing blood pressures, fasting glucose levels and body mass indices in patients with established atherothrombotic disease.MethodThis randomized controlled pilot trial included outpatients who were over 45 years of age with atherothrombotic cardiovascular disease. Group A, who received the Brazilian Cardioprotective Diet Program, had weekly sessions with dietitians. Groups B and C received the usual dietary therapy that is given to patients with cardiovascular diseases as proposed by the Brazilian guidelines. This diet had the same nutrient profile as that given to Group A, but it was customized by the integration of typical Mediterranean foods. The difference between Groups B and C was the number of sessions with the dietitian. Group B received weekly sessions, while group C only had monthly sessions. ClinicalTrials.gov: NCT 01453166.ResultsThere was a greater reduction in systolic (7.8%) and diastolic (10.8%) blood pressures in Group A compared with Group B (2.3% and 7.3%), and Group C (3.9% and 4.9%, respectively). Fasting glucose decreased by 5.3% and 2% in Groups A and B, respectively. Fasting glucose increased by 3.7% in Group C. The BMIs decreased by 3.5% and 3.3% in Groups A and B, respectively. Group C did not present with any changes in BMI. However, none of these data showed statistical differences between the groups, which is methodologically acceptable in pilot trials.ConclusionsThe Brazilian Cardioprotective Diet Program seems to be more effective in reducing blood pressures, fasting glucose levels, weights and BMIs in patients with previous cardiovascular disease compared with the diet that has been proposed by the Brazilian guidelines.

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