• Internal medicine · Dec 2024

    Case Reports

    Drug-induced Steatohepatitis Caused by Long-term Use of Topical Steroids for Atopic Dermatitis: A Case Report.

    • Yuki Tamura, Atsushi Naganuma, Yuhei Suzuki, Sanae Uehara, Takashi Hoshino, Takeshi Hatanaka, Nobuyuki Shibusawa, Akihito Uehara, Akira Ogawa, Satoru Kakizaki, and Toshio Uraoka.
    • Department of Gastroenterology, NHO Takasaki General Medical Center, Japan.
    • Intern. Med. 2024 Dec 1; 63 (23): 316531703165-3170.

    AbstractAtopic dermatitis is common in children and often treated with topical corticosteroids (TCs). A boy in his late teens who had been using TCs for atopic dermatitis was diagnosed with liver damage during a health checkup. A medical examination revealed severe steatotic liver disease and elevated liver enzyme levels despite the absence of typical symptoms such as central obesity. After discontinuation of TCs, an improvement in liver enzyme levels was observed, leading to the diagnosis of drug-induced steatohepatitis. This case underscores the potential liver risks associated with prolonged TC use in children, highlighting the need for parental education.

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