• Vaishnavee Sreeharan, Hugo Madden, John Tayu Lee, Christopher Millett, and Azeem Majeed.
• Department of Primary Care and Public Health, Imperial College, London, Reynolds Building, Charing Cross Campus, London, UK. vaishnavee@doctors.org.uk
• Br J Gen Pract. 2013 Sep 1; 63 (614): e649e653e649-53.

BackgroundAntidepressant prescribing rates in England have been increasing since the 1970s. The impact of the Improving Access to Psychological Therapies (IAPT) initiative on antidepressant prescribing rates is unknown.AimTo investigate the impact of the establishment of IAPT services on antidepressant prescribing rates in primary care trusts (PCTs) in England.Design And SettingA longitudinal time-series analysis, using PCT-level data from 2008 to 2011 set in England.MethodA time-series analysis was conducted using PCT-level prescription data, dates of establishment of IAPT services, and covariate data for age, sex, and socioeconomic status. Statistical analysis was carried out using analysis of variance and a random-effect negative binomial model.ResultsAntidepressant prescribing rates in England increased by 10% per year during the study period (adjusted rate ratio = 1.10, 95% CI = 1.09 to 1.10). The implementation of IAPT services had no significant effect on antidepressant prescribing (adjusted rate ratio = 0.99, 95% CI = 0.99 to 1.00).ConclusionIntroduction of a large-scale initiative to increase provision of psychological therapies has not curbed the long-term increased prescribing of antidepressants in England.

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