• Medicina clinica · May 2024

    Case Reports

    Appendecular actinomycosis: A case series of 14 patients.

    • Ramazan Serdar Arslan, Yavuz Savaş Koca, Reşad Beyoğlu, and Ahmet Emre Yenipazar.
    • Servergazi State Hospital Department of General Surgery, Denizli, Turkey. Electronic address: r.serdar.arslan@gmail.com.
    • Med Clin (Barc). 2024 May 31; 162 (10): 500504500-504.

    ObjectiveThis study aims to assess the clinical, radiological, and histological characteristics of Actinomyces infection identified in appendectomy specimens.Material And MethodsBetween January 2013 and November 2023, 5834 patients underwent appendectomy in our clinic, and their pathology reports were retrospectively reviewed.ResultsActinomyces appendicites were reported in 14 specimens (0.23%). It was determined that appendectomy was performed in only 10 patients (71.4%), ileocecal resection was performed in two patients (14.2%) and right hemicolectomy in two patients (14.2%). The operations on five patients were performed by laparoscopy, and the operations on the other nine patients were performed by open surgery. Laparoscopy was started in three patients and converted to open surgery due to suspicion of an ileocecal mass and cecal perforation. It was found that the white blood cell count of three patients was within the normal range of reference (8-9.77mg/dL); leukocytosis was detected in other patients (10.2-18.7mg/dL). C-reactive protein was normal in one patient and high in the rest of the patients. While the first-hour erythrocyte sedimentation rate was normal in five patients, it was found to be high in the other patients. Findings on radiological imaging were reported as acute appendicitis, appendicular plastron, and ileocecal mass. As a result of the pathology findings, the patients were given oral penicillin or semi-synthetic penicillin derivatives during one month.ConclusionIleocecal and appendecular actinomycosis are rare, and preoperative diagnosis is difficult. A definitive diagnosis is usually made after a histopathological examination. After surgery, long-term antimicrobial treatment of the patient is possible with penicillin.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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