• Soffia Khursheed, Samia Wazir, Muhammad Khurram Saleem, Ayesha Isani Majeed, Mumtaz Ahmad, KhanQudsia UmairaQUCMH Lahore Medical College, Lahore, Pakistan., Arzu Jadoon, Amna Akbar, Sarosh Khan Jadoon, Sabahat Tasneem, Humayun Saleem, KhanMohammad SaleemMSChief Consultant Physician/Head of Department of Medicine DHQ Teaching, Hospital Kotli AJK, Kotli, Pakistan., and Sarosh Alvi.
• Pakistan Institute of Medical Science, Islamabad, Pakistan.
• Medicine (Baltimore). 2024 Apr 12; 103 (15): e37787e37787.

AbstractTuberculosis (TB) remains a serious problem for public health and a leading cause of death after COVID-19 and superior to even HIV/AIDS. It is a social health issue and can cause stigma and economic loss as the person cannot perform professionally due to lethargy caused by disease. It is a retrospective study done on data from National TB program Muzaffarabad chapter. The details were noted on SPSS and analysis was done to find important demographic characteristics. The total number of patients was 3441; among which 48.76% were males. Most of them (81.11%) belonged to the Muzaffarabad division of Azad Jammu and Kahmir (AJK). The microbiologically or culture positive cases were 440. Rifampicin resistance was present in 147 cases, further categorized as high (n = 143), very high (n = 3), or true positive (n = 1) resistance. Muti drug resistance was found in 19 cases. The microscopy culture is more sensitive (AUC = 0.511) than MTB/RIF or serology (AUC = 0.502) according to ROC. The rate of positive smear results is not very satisfactory in the present study as it cannot detect dormant or latent cases. There is a need to establish more sensitive tests for detection of cases and more research to combat the disease.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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