• Lancet neurology · May 2024

    Review

    Improving epilepsy diagnosis across the lifespan: approaches and innovations.

    • Jacob Pellinen, Emma C Foster, Jo M Wilmshurst, Sameer M Zuberi, and Jacqueline French.
    • Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA. Electronic address: Jacob.Pellinen@cuanschutz.edu.
    • Lancet Neurol. 2024 May 1; 23 (5): 511521511-521.

    AbstractEpilepsy diagnosis is often delayed or inaccurate, exposing people to ongoing seizures and their substantial consequences until effective treatment is initiated. Important factors contributing to this problem include delayed recognition of seizure symptoms by patients and eyewitnesses; cultural, geographical, and financial barriers to seeking health care; and missed or delayed diagnosis by health-care providers. Epilepsy diagnosis involves several steps. The first step is recognition of epileptic seizures; next is classification of epilepsy type and whether an epilepsy syndrome is present; finally, the underlying epilepsy-associated comorbidities and potential causes must be identified, which differ across the lifespan. Clinical history, elicited from patients and eyewitnesses, is a fundamental component of the diagnostic pathway. Recent technological advances, including smartphone videography and genetic testing, are increasingly used in routine practice. Innovations in technology, such as artificial intelligence, could provide new possibilities for directly and indirectly detecting epilepsy and might make valuable contributions to diagnostic algorithms in the future.Copyright © 2024 Elsevier Ltd. All rights reserved.

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