Lesson of the month 1: Septic arthritis with normal acute phase

Clin Med (Lond) · Jun 2017

Case Reports

Lesson of the month 1: Septic arthritis with normal acute phase reactants and white cell count in a patient receiving tocilizumab.

Septic arthritis represents 8-27% of cases of monoarthritis presenting to the emergency department. Tocilizumab is an interleukin-6 blocking monoclonal antibody with the mechanistic potential to interfere with the body's normal inflammatory response to an infectious insult. We present a case of septic arthritis with a normal white cell count, C-reactive protein, erythrocyte sedimentation rate and fibrinogen in a patient treated with tocilizumab.

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- Richard Conway, Carl Orr, and Geraldine M McCarthy.
- Mater Misericordiae University Hospital and CARD Newman Research Fellow, University College Dublin, Dublin, Ireland drrichardconway@gmail.com.
- Clin Med (Lond). 2017 Jun 1; 17 (3): 280281280-281.
AbstractSeptic arthritis represents 8-27% of cases of monoarthritis presenting to the emergency department. Tocilizumab is an interleukin-6 blocking monoclonal antibody with the mechanistic potential to interfere with the body's normal inflammatory response to an infectious insult. We present a case of septic arthritis with a normal white cell count, C-reactive protein, erythrocyte sedimentation rate and fibrinogen in a patient treated with tocilizumab.© Royal College of Physicians 2017. All rights reserved.

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Lesson of the month 1: Septic arthritis with normal acute phase reactants and white cell count in a patient receiving tocilizumab.

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