• Clin Med (Lond) · Dec 2017

    Review Case Reports

    Lesson of the month 1: Obesity hypoventilation (Pickwickian) syndrome: a reversible cause of severe pulmonary hypertension.

    • Frazer Warricker, Zafir Islam, and Benoy N Shah.
    • Department of Cardiology, University Hospital Southampton, Southampton, UK.
    • Clin Med (Lond). 2017 Dec 1; 17 (6): 578581578-581.

    AbstractObesity hypoventilation syndrome (OHS) is a condition in which an individual with a body mass index >30 kg/m2 develops daytime alveolar hypoventilation (defined as a resting PaCO2 >45 mmHg) that cannot be attributed to other pathologies. It is a condition with increasing prevalence and rising cost to healthcare systems worldwide. Right heart failure and pulmonary hypertension are well-known complications of this syndrome. Here, we present the case of a female patient with OHS who presented to our centre with severe pulmonary hypertension, which resolved with appropriate treatment. We also review this clinical condition and its diagnosis and management.© Royal College of Physicians 2017. All rights reserved.

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