• Clin Med (Lond) · Oct 2016

    Case Reports

    Lesson of the month 1: Autoinflammatory syndromes - an unusual cause of pyrexia of unknown origin.

    • Ravi Varma, Gary Campbell, and Helen Baxendale.
    • Norfolk and Norwich University Hospital NHS Foundation Trust, Norwich, UK ravi.varma@hotmail.co.uk.
    • Clin Med (Lond). 2016 Oct 1; 16 (5): 488490488-490.

    AbstractAutoinflammatory diseases are disorders of innate immunity and are characterised by recurring and unprovoked episodes of inflammation. We present a case of episodic pyrexia, associated with a significant inflammatory response, in a young man in whom the cause had remained unexplained since infancy. He was eventually diagnosed with hyperimmunoglobulinaemia D syndrome (HIDS); one of the autoinflammatory syndromes.© Royal College of Physicians 2016. All rights reserved.

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