• Elizabeth M Yano, Lisa V Rubenstein, Melissa M Farmer, Bruce A Chernof, Brian S Mittman, Andrew B Lanto, Barbara F Simon, Martin L Lee, and Scott E Sherman.
• VA Greater Los Angeles HSR&D Center of Excellence, Sepulveda VA Ambulatory Care Center (152), 16111 Plummer Street, Sepulveda, CA 91343, USA.
• Health Serv Res. 2008 Oct 1;43(5 Pt 1):1637-61.

ObjectiveTo evaluate the impact of a locally adapted evidence-based quality improvement (EBQI) approach to implementation of smoking cessation guidelines into routine practice.Data Sources/Study SettingWe used patient questionnaires, practice surveys, and administrative data in Veterans Health Administration (VA) primary care practices across five southwestern states.Study DesignIn a group-randomized trial of 18 VA facilities, matched on size and academic affiliation, we evaluated intervention practices' abilities to implement evidence-based smoking cessation care following structured evidence review, local priority setting, quality improvement plan development, practice facilitation, expert feedback, and monitoring. Control practices received mailed guidelines and VA audit-feedback reports as usual care.Data CollectionTo represent the population of primary care-based smokers, we randomly sampled and screened 36,445 patients to identify and enroll eligible smokers at baseline (n=1,941) and follow-up at 12 months (n=1,080). We used computer-assisted telephone interviewing to collect smoking behavior, nicotine dependence, readiness to change, health status, and patient sociodemographics. We used practice surveys to measure structure and process changes, and administrative data to assess population utilization patterns.Principal FindingsIntervention practices adopted multifaceted EBQI plans, but had difficulty implementing them, ultimately focusing on smoking cessation clinic referral strategies. While attendance rates increased (p<.0001), we found no intervention effect on smoking cessation.ConclusionsEBQI stimulated practices to increase smoking cessation clinic referrals and try other less evidence-based interventions that did not translate into improved quit rates at a population level.© Health Research and Educational Trust.

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