• Clin Med · Apr 2009

    Case Reports

    Chorea.

    • Michele T M Hu, Richard Butterworth, Gavin Giovannoni, Andrew Church, and Stephen Logsdail.
    • Milton Keynes Hospital NHS Foundation Trust. michele.hu@mkhospital.nhs.uk
    • Clin Med. 2009 Apr 1; 9 (2): 188189188-9.

    AbstractTwo weeks after starting the oral contraceptive pill, a 16-year-old girl developed increasingly violent chorea and an evolving psychosis with prominent hallucinations, ideas of reference, and paranoia. An erythematous skin rash subsequently developed and Sydenham's chorea (SC) was diagnosed. Following neuroleptic medication and steroids, her chorea and psychosis subsided. This case illustrates that severe psychotic features can occur in SC. It is recommended that antistreptolysin O titres and antibasal ganglia antibodies are checked early in patients with evolving movement disorders and prominent neuropsychiatric features, as the window for modifying the course of this immune-mediated disorder may be narrow.

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