• Hernani Pinto de Lemos and Alvaro Nagib Atallah.
• Brazilian Cochrane Center, Universidade Federal de São Paulo-Escola Paulista de Medicina, São Paulo, Brazil. cochrane.dmed@epm.br
• Sao Paulo Med J. 2007 Jul 5; 125 (4): 242245242-5.

Context And ObjectiveThe safety and efficacy of drug-eluting stents reduce the need for surgical revascularization. The objective of the present study was to investigate whether paclitaxel or rapamycin-eluting stent are effective in avoiding the need for coronary-artery bypass grafting.MethodsThis was a systematic review of the literature using the methodology of the Cochrane Collaboration. The type of study considered was controlled randomized trials; the type of intervention was drug-eluting or bare-metal stents; and the main outcome investigated was coronary-artery bypass grafting.ResultsThe ten studies included in this systematic review did not show any statistically significant difference between the drug-eluting stents and the bare-metal stents with regard to the outcome of coronary-artery bypass grafting (confidence interval: 0.31 to 1.42).ConclusionThe surgical revascularization rate was not reduced by the use of drug-eluting stents.

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