• Br J Anaesth · Oct 1998

    Randomized Controlled Trial Clinical Trial

    Assessment of intubating conditions in adults after induction with propofol and varying doses of remifentanil.

    • S Grant, S Noble, A Woods, J Murdoch, and A Davidson.
    • Glasgow University, Department of Anaesthesia, Glasgow Royal Infirmary.
    • Br J Anaesth. 1998 Oct 1; 81 (4): 540-3.

    AbstractWe have assessed intubating conditions in three groups of 60 ASA I or II patients after induction of anaesthesia with propofol 2 mg kg-1 and remifentanil 0.5, 1.0 or 2.0 micrograms kg-1. Tracheal intubation was graded according to ease of laryn-goscopy, position of the vocal cords, coughing, jaw relaxation and movement of the limbs. Intubation was successful in 80%, 90% and 100% of patients after remifentanil 0.5, 1.0 or 2.0 micrograms kg-1, respectively. Overall intubating conditions were regarded as acceptable in 20%, 50% and 80% of patients, respectively. All three groups had a decrease in arterial pressure after induction but there was no difference between groups. The decrease in arterial pressure was not regarded as clinically significant. Intubating conditions were best after induction with remifentanil 2 micrograms kg and propofol 2 mg kg-1.

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