• J Headache Pain · Dec 2007

    Case Reports

    Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna.

    • Sindhu Ramchandren and David S Liebeskind.
    • Department of Neurology, University of Michigan at Ann Arbor, 300 North Ingalls St., #3D06, Ann Arbor, MI 48109, USA. sindhur@med.umich.edu
    • J Headache Pain. 2007 Dec 1; 8 (6): 342344342-4.

    AbstractHyperostosis frontalis interna (HFI) has been reported in older women, but reports in men are rare. We present a novel case of migraine headache in a gentleman with Klinefelter's syndrome and HFI, along with a discussion of possible pathophysiologic mechanisms underlying both the headache and the HFI.

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