• J Headache Pain · Oct 2010

    Case Reports

    Are Cox-2 drugs the second line option in indomethacin responsive headaches?

    • Jesús Porta-Etessam, Marialuz Cuadrado, Octavio Rodríguez-Gómez, Sara García-Ptacek, and Cristina Valencia.
    • Headache Unit, Hospital Universitario Clínico San Carlos, C/ Andrés Torrejón 15, Madrid, Spain. jporta@yahoo.com
    • J Headache Pain. 2010 Oct 1; 11 (5): 405407405-7.

    AbstractParoxysmal hemicrania and hemicrania continua are both indomethacin-responsive headaches. Although indomethacin use to be well tolerated, some patients developed gastrointestinal side effects. We report four cases of hemicrania continua and a patient suffering chronic paroxysmal hemicrania completely responsive to celecoxib. In our experience celecoxib is a good option treatment for patients suffering from hemicrania continua or chronic paroxysmal hemicranea that presents indomethacin adverse effects.

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