• Wei-Chih Su, Tsung-Tai Chen, Chien-Hsien Wu, Ling-Na Shih, Chih-Kuang Liu, and HsuehYa-Seng ArthurYACentre for Health Policy, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, VIC, Australia..
• Department of Gastroenterology, Taipei Tzu-Chi Hospital, New Taipei City, Taiwan.
• J Formos Med Assoc. 2024 Oct 1; 123 (10).

BackgroundPatient-centered care (PCC) is a crucial objective for enhancing healthcare in the 21st century. PCC has demonstrated effectiveness in caring for patients with chronic conditions. However, the process from PCC to patient outcomes has not been thoroughly studied, particularly for patients with chronic hepatitis.ObjectiveTo investigate the relationship between PCC and the outcomes of hepatitis patients and determine the key mediator in the connection between PCC and outcomes.MethodsA cross-sectional study was conducted from October to December 2016 in four hospitals in northern Taiwan. Patients with chronic viral hepatitis were assessed for five PCC factors: autonomy support, goal setting, coordination of care, information/education/communication, and emotional support. Trust in the physician, patient adherence, and patient activation (PA) were selected as mediators, with health-related quality of life (HRQoL) as the patient outcome. Pathway analysis was applied to examine the correlation.ResultsIn total, 496 chronic hepatitis patients were included in the study. The pathway analysis revealed that autonomy support (β = 0.007, p = 0.011), information/education/communication (β = 0.009, p = 0.017), and emotional support (β = 0.001, p = 0.011) correlated with better HRQoL. The effects of PCC factors are fully mediated by trust in physicians, patient adherence, and PA. Among them, PA is the key factor in the process of PCC.ConclusionFor chronic viral hepatitis care, PCC should be introduced into clinical practice for better HRQoL, and PA is a key mediator.Copyright © 2024 Formosan Medical Association. Published by Elsevier B.V. All rights reserved.

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