• Chao Yang, Mingjun Luo, Langlang Li, and Qizhi Yang.
• Department of Urology, 302 Hospital of China Guizhou Aviation Industry Group, Anshun, Guizhou, China.
• Medicine (Baltimore). 2024 May 3; 103 (18): e36130e36130.

RationaleSpontaneous renal rupture is an uncommon disease, it usually occurs after upper urinary calculi-related operation treatment or renal tumor. This disease caused by factor VII deficiency has rarely reported.Patient ConcernsA 49-year-old woman came to our hospital with on the left flank pain and gross hematuria that had persisted for 10 days. The patient had no recent history of waist and abdominal trauma or surgical history recently.DiagnosesAn outside computed tomography (CT) examination revealed left renal rupture before arriving at our hospital, but she was not treated. Further laboratory examination revealed that the patient condition was turned out to be hemophilia caused by factor VII deficiency.InterventionWe have used both internal and external drainage methods, and supplemented with coagulation factor.OutcomeAfter 9 months of follow-up, it was observed that the left renal hematoma and urinary extravasation was completely absorbed.LessonsSpontaneous renal rupture for hemophilia is a clinical emergency. When spontaneous renal rupture is associated with abnormal coagulation function, and the coagulation function cannot be corrected by conventional treatment, the possibility of hemophilia needs to be considered, and the type of hemophilia needs to be further defined. This case indicates a successful resolution of spontaneous renal rupture, it can provide guiding value for our clinical practice.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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