• Shinichiro Chujo, Hisashi Matsubara, Yoshitusgu Matsui, Kumiko Kato, and Mineo Kondo.
• Department of Ophthalmology, Mie University Graduate School of Medicine, Mie, Japan.
• Medicine (Baltimore). 2024 May 17; 103 (20): e38150e38150.

RationaleAcute retinal necrosis (ARN) was first reported in 1971 by Urayama et al as an acute uveitis accompanied by retinal arteritis and white retinal lesions in the peripheral retina that can progress to a rhegmatogenous retinal detachment (RRD). We have experienced a case of ARN that, unlike the common developmental course to an RRD associated with ARN, progressed to proliferative vitreoretinopathy (PVR) involving the entire retina in 2 days. The purpose of this report is to present our findings in the case of ARN with an atypical rapid time course.Patient ConcernsThe patient was a 56-year-old woman who was treated for uveitis of unknown origin by her primary care physician. She was referred to our hospital because of a worsening of the fundus findings.DiagnosisFundus examination in our hospital revealed vitreous opacities in the right eye, yellowish-white lesions extending around the retina, and some retinal hemorrhages. Because the retinal changes suggested ARN, we performed a polymerase chain reaction of the anterior atrial fluid and detected varicella-zoster virus. Then, the diagnosis of ARN was confirmed, and treatment was begun. At 1 month and a half after beginning the treatment, focal retinal traction was observed in the right fundus. Two days later, a circumferential PVR and a total retinal detachment were detected.InterventionsWe then performed vitrectomy with an encircling buckle and a silicone oil tamponade.OutcomesOur examination 6 months postoperatively showed that the retina was attached and the BCVA was 20/200.LessonsOur findings of a case of ARN showed that the progression from a local vitreous traction to a full circumferential PVR can develop in 2 days.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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