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Journal of critical care · Oct 2024
Echocardiography predictors of sustained sinus rhythm after cardioversion of supraventricular arrhythmia in patients with septic shock.
- M Balik, P Waldauf, M Maly, T Brozek, J Rulisek, M Porizka, R Sachl, M Otahal, P Brestovansky, E Svobodova, M Flaksa, Z Stach, J Horejsek, L Volny, I Jurisinova, A Novotny, P Trachta, J Kunstyr, P Kopecky, T Tencer, J Pazout, A Krajcova, and F Duska.
- Department of Anaesthesiology and Intensive Care, 1(st) Faculty of Medicine, Charles University and General University Hospital in Prague, Czechia. Electronic address: martin.balik@vfn.cz.
- J Crit Care. 2024 Oct 1; 83: 154832154832.
PurposeThe echocardiography parameters may predict the maintenance of sinus rhythm after cardioversion of a supraventricular arrhythmia (SVA).Materials And MethodsPatients in septic shock with onset of an SVA, normal to moderately reduced LV systolic function (EF_LV˃̳35%) and on a continuous noradrenaline of <1.0 μg/kg.min were included. Echocardiography was performed at the arrhythmia onset, 1 h and 4 h post cardioversion on an infusion of propafenone or amiodarone.ResultsCardioversion was achieved in 96% of the 209 patients within a median time of 6(1.8-15.6)h, 134(64.1%) patients experienced at least one SVA recurrence after cardioversion. At 4 h the left atrial emptying fraction (LA_EF, cut-off 38.4%, AUC 0.69,p˂0.001), and transmitral A wave velocity-time-integral (Avti, cut-off 6.8 cm, AUC 0.65,p = 0.001) showed as limited predictors of a single arrhythmia recurrence. The LA_EF 44(36,49)%, (p = 0.005) and the Avti 8.65(7.13,9.50)cm, (p < 0.001) were associated with sustained sinus rhythm and decreased proportionally to increasing numbers of arrhythmia recurrences (p < 0.001 and p = 0.007, respectively). The enlarged left atrial end-systolic diameter at the arrhythmia onset (p = 0.04) and elevated systolic pulmonary artery pressure at 4 h (p = 0.007) were weak predictors of multiple(˃3) recurrences.ConclusionThe LA_EF and Avti are related to arrhythmia recurrences post-cardioversion suggesting potential guidance to the choice between rhythm and rate control strategies.Trial RegistrationClinicalTrials.gov Identifier: NCT03029169, registered on 24th of January 2017.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.
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