• Gurushankari Balakrishnan, Chandra Kumar Krishnan, Vijay Sundar Ilangovan, Krishna Suresh, Ramakrishnan Ayloor Seshadri, and Anand Raja.
• Department of Surgical Oncology, Cancer Institute- Women India Association (WIA), Chennai, India.
• World Neurosurg. 2024 Oct 1; 190: 333733-37.

BackgroundPrimary malignant tumors of the spine are rare and most commonly occur in lumbar and thoracic vertebrae. We report a rare case of retroperitoneal chondrosarcoma of L3 that was managed with sagittal en bloc spondylectomy following chemoradiation.Case DescriptionA 26-year-old woman was evaluated for abdominal pain with contrast-enhanced computed tomography of the abdomen and pelvis, which revealed a soft tissue retroperitoneal mass arising from L3. She underwent laparotomy and biopsy, which revealed chondrosarcoma, and she received chemoradiation over a period of 28 weeks 6 days. After repeat imaging, she underwent single-stage combined approach sagittal en bloc spondylectomy of retroperitoneal chondrosarcoma of L3 with right nephrectomy and spine reconstruction. At 3-year follow-up, there was no evidence of recurrence on contrast-enhanced computed tomography of the abdomen and pelvis. She demonstrated no gait abnormality or spinal deformity.ConclusionsSagittal en bloc spondylectomy is a preferred surgical approach for eccentrically placed spinal tumors that offers better oncological and functional outcomes.Copyright © 2024 Elsevier Inc. All rights reserved.

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