• World Neurosurg · Aug 2024

    Differentiation of the Intradural Extramedullary Spinal Tumors, Schwannomas and Meningiomas, Utilizing the Contrast Ratio as a Quantitative Magnetic Resonance Imaging Method.

    • Toshio Nakamae, Naosuke Kamei, Takayuki Tamura, Toshiaki Maruyama, Kazuto Nakao, Fadlyansyah Farid, Hiroki Fukui, and Nobuo Adachi.
    • Department of Orthopaedic Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan. Electronic address: toshinakamae623813@yahoo.co.jp.
    • World Neurosurg. 2024 Aug 1; 188: e320e325e320-e325.

    BackgroundSchwannomas and meningiomas are the most common intradural extramedullary spinal tumors; however, differentiating between them using magnetic resonance imaging (MRI) is a frequent challenge. In this study, we aimed to investigate the use of the contrast ratio (CR) as a quantitative MRI method in the differentiation of schwannomas and meningiomas.MethodsWe analyzed the data of patients with intradural extramedullary spinal tumors who underwent surgery and were diagnosed with either schwannomas or meningiomas by histopathological analysis. Regions of interest were set for the entire spinal tumor on T2-weighted sagittal MRI. To obtain the CR values of spinal tumors (CRtumor), we used the signal intensity (SI) values of the tumor (SItumor) and spinal cord (SIcord) according to the following formula: [CRtumor = (SItumor-SIcord)/(SItumor+SIcord)].ResultsThe study included 50 patients (23 males and 27 females) with a mean age of 61.5 years old (11-85 years old). Histopathological analysis revealed that 33 and 17 patients were diagnosed with schwannomas and meningiomas, respectively. The mean CR values of the schwannomas and meningiomas were 0.3040 ± 0.1386 and 0.0173 ± 0.1929, respectively. The CR value of the schwannomas was statistically significantly higher than that of meningiomas (P < 0.01). The cutoff CR value obtained from the receiver operating characteristic curve was 0.143, with a specificity and sensitivity of 90.9% and 88.2%, respectively. Furthermore, the value for the area under the receiver operating characteristic curve was 0.925 (95% confidence interval: 0.852-0.998).ConclusionsThe evaluation of CRs by using MRI to distinguish between schwannomas and meningiomas is a beneficial quantitative tool.Copyright © 2024. Published by Elsevier Inc.

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