• C Lorut, A Rabbat, G Chatelier, A Lefevre, N Roche, J F Regnard, and G Huchon.
• Service de pneumologie et reanimation, Hôpital Hôtel Dieu, Paris, France. christine.lorut@htd.ap-hop-paris.fr
• Rev Mal Respir. 2005 Feb 1;22(1 Pt 1):127-34.

BackgroundRespiratory complications are common following pulmonary resection and cause a significant mortality. The use of non-invasive ventilation (NIV) in acute respiratory insufficiency (ARI) is now well recognised. The prophylactic use of NIV in the absence of ARI and/or hypercapnia may be equally justified for the physiological benefits expected in the post-operative period following pulmonary surgery. The aim of our study therefore is to evaluate the effectiveness of NIV in the prevention of pulmonary complications in the immediate post-operative care of patients with moderate and severe COPD.MethodsIt will be a multicentre, prospective, randomised, parallel, open ended study of patients with moderate and severe COPD admitted to hospital for pulmonary resection.Expected ResultsTo determine whether the setting up of NIV immediately post-operatively reduces the incidence of acute respiratory events (acute respiratory insufficiency) and to identify any sub-groups who receive greater benefit from NIV. This study should establish the place of NIV in the immediate post operative care following pulmonary resection.

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