• Osnat Zmora, Ron Beloosesky, Ayala Gover, and Moshe Bronshtein.
• Department of Pediatric Surgery, Assaf Harofeh Medical Center, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
• Isr Med Assoc J. 2019 Feb 1; 21 (2): 858785-87.

BackgroundUnilateral renal agenesis is a rare finding. There are no large-scale studies reporting this finding in early pregnancy.ObjectivesTo evaluate the incidence of unilateral renal agenesis (URA) and of associated anomalies diagnosed by early prenatal trans-vaginal sonography.MethodsWe performed a retrospective chart review of all 59,382 trans-vaginal scans performed at 14-16 weeks gestation by a single operator at different clinics during the period 1994-2013.ResultsThe incidence of URA was 1:1212 (49/59382 cases). Associated anomalies were diagnosed in 22 cases (45%). Renal anomalies were diagnosed in 22.4%. Extra-renal anomalies (with exclusion of a single umbilical artery or nuchal edema as isolated findings) were diagnosed in 24.5%. Ambiguous genitalia were diagnosed in 8.2%.ConclusionsURA is a rare finding in early trans-vaginal sonography. Associated anomalies are very common and should be sought.

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